Analytical developments over the last few decades have significantly improved the capabilities to analyse hydrogen and oxygen isotopes in various environmental materials (e.g., specific organic compounds from algae and plants, ambient water, leaf water as well as proxy materials in climatic archives). In conjunction with the outstanding possibility to investigate hydrogen and oxygen isotope compositions by modelling efforts, these studies promise great potential to furthering our understanding of fractionation processes, biosynthetic effects and paleo-climatological reconstructions. To deliver a state-of-the-art overview of ongoing activities, we invite contributions related to the development, calibration, and application of related isotope analyses as well as appropriate modelling studies.