The discovery of non-mass dependent isotope fractionation processes in the laboratory and in nature have revolutionised the way stable isotope measurements can be applied. Previously neglected minor isotope ratios such as 17O/16O, 33S/32S, 36S/32S, etc. have found a justification to be used. The aim of this session is to highlight the latest results and discoveries in this rapidly expanding field. While oxygen and sulphur have led the non-traditional (often subsumed as "mass-independent") isotope fractionation world, other elements and isotope systems (e. g., mercury, tin, cadmium) are emerging along with an improved understanding of the quantum-chemical processes responsible for these anomalies. For this session, we invite contributions from all fields (hydrology, atmospheric chemistry, oceanography, biogeochemistry, cosmochemistry, geology, etc.) using field observations, laboratory experiments, theory or modelling, laboratory experiments of isotope anomalies and non-mass dependent isotope fractionation processes to explore our past, present, future environment and universe.