Land-atmosphere interactions include a variety of critical feedbacks between radiative, hydrological, and biogeochemical processes resulting in complex exchanges of energy and matter that influence the overall Earth system and its climate. The observation, understanding and prediction of such processes and their impacts have been hindered in the past by the lack of suitable data at the required spatial and temporal scales. Over the last few years, Earth-Observation (EO) data integrated with in situ networks and within suitable models have demonstrated the potential to become a major tool for observing key variables and characterizing the main processes governing land-atmosphere interactions at global to local scales. This session focuses on studies that integrate EO data together with in situ observations into state-of-the-art models to increase the scientific understanding of main land-atmosphere interactions and their impacts on the Earth system and climate.