The proposed session is an important part of the ongoing IGCP 610 project “From the Caspian to Mediterranean: Environmental Change and Human Response during the Quaternary.” The area under study encompasses the Eurasian intercontinental basins of the Caspian, Black, Marmara, Aegean, and Eastern Mediterranean seas with their connecting straits and coasts. The purpose of the session is to bring together scientists from developing and developed countries to coordinate their research and to correlate their obtained results in the exact and historical sciences in order to evaluate the influence of environmental cataclysms on human adaptive strategies in the area under study. This multidisciplinary session will be organized along the following dimensions: 1. The geological dimension will examine the sedimentary record of vertical sea-level fluctuations and lateral coastline change. 2. The paleoenvironmental dimension will integrate paleontological, palynological, and sedimentological records to reconstruct paleolandscapes. 3. The archaeological dimension will investigate cultural remains. 4. The paleoanthropological dimension will study responses of different Homo species to environmental change. 5. The mathematical dimension will provide GIS-aided mathematical modeling of climate and sea-level changes, and human dispersal linked to paleoenvironmental variation that can be meaningfully compared with current global changes.