Envisioning desirable futures for biodiversity requires not only compelling narratives but also rigorous and operational frameworks that can be applied across contexts and scales. This session highlights the Nature Futures Framework (NFF) as a methodological foundation for developing biodiversity-centric scenarios and translating them into actionable strategies for sustainability and governance. Presentations will demonstrate how the NFF has been, or could be, employed to construct scenarios that connect local realities with global drivers, integrate social, ecological, and governance dimensions across scales, and embed plural knowledge systems—including Indigenous and local perspectives—into the scenario development process. A key focus will be on translating these scenarios into practical pathways for policy and decision-making. By concentrating on methodological innovation, the session will illuminate both the analytical strengths and the practical challenges of applying nature-focused perspectives, including the treatment of uncertainty, the integration of diverse disciplinary approaches and knowledge systems, and the challenge of scaling from local case studies to national strategies. Through critical reflection on ongoing applications, the session aims to provide concrete insights into the use of the NFF across scales, clarify its methodological strengths and limitations, foster exchange on integrating plural knowledge systems into scenario work, and identify opportunities for embedding the NFF into governance and policy frameworks. In doing so, it will strengthen collaboration among researchers, practitioners, and decision-makers while inspiring methodological advances for biodiversity futures research.