The World's largest rivers dominate Earth's drainage basins, controlling terrestrial water and sediment flux to the oceans and in turn govern the deposition of the majority of alluvial sedimentation sequences. However, surprisingly little is known about the morphodynamics and sedimentology of large rivers or how relations between process-form-deposit may vary across scales of river size. Recent technological advances are now allowing us to quantify such process-form-deposit relations in large rivers and this session aims to bring together interdisciplinary researchers who are: (i) advancing methods for quantifying flow structure and sediment transport in large rivers, (ii) studying their morphodynamics and sedimentary deposits, and (iii) modelling sediment transport processes and morphological change at large spatial scales.