The geological record provides insight into how climate processes may operate and evolve in a high CO2 environment and the nature of the climate system during a turnover from icehouse to greenhouse state — a transition that may potentially occur in the near future. In recent years we have seen major advances in many geochemical techniques and an increase in the complexity of Earth System Models. The aim of this session is to share progress in our understanding of global changes occurring during the pre-Quaternary based on the integration of geochemical/paleobotanical/sedimentological techniques and numerical models. Specifically, we encourage submissions describing research in which both model and data approaches are embedded. We invite abstracts that reconstruct Earth’s climate from the Cambrian to the Pliocene, investigate how the interconnections of the key surface reservoirs (vegetation-ocean-atmosphere-cryosphere-biogeochemistry) impact climate, and identify tipping points and thresholds. Pertinent themes may include greenhouse-icehouse transitions and intervals testifying for extreme changes.