The Caribbean region is an ideal natural laboratory for studying long- to short-term deformation processes along plate boundaries. Indeed, the Caribbean plate has been individualized since at least 140 Ma and its boundaries are still deforming today. Earthquakes in the Caribbean are a stark reminder of the dangers posed by active deformation along the densely populated boundaries of the Caribbean plate, where vulnerability is often extremely high. Over the past decades, these boundaries have been the focus of extensive international research, providing new insights into the geodynamics of the region and the broader geological processes occurring in subduction and strike-slip zones. This includes studies on fluids, seismicity, deformation partitioning, and mantle dynamics, as well as the reorganization of plate boundaries in response to changes in plate kinematics—such as suturing, the migration, extinction, or initiation of volcanic arcs, and deformation or vertical movement.