Ice sheets play an active role in the climate system by amplifying, pacing, and potentially driving global climate change over a wide range of time scales. The impact of interactions between ice sheets and climate include changes in atmospheric and ocean temperatures and circulation, global biogeochemical cycles, the global hydrological cycle, vegetation, sea level, and land-surface albedo, which in turn cause additional feedbacks in the climate system. This session will present data and modelling results that examine ice sheet interactions with other components of the climate system over several time scales. Among other topics, issues to be addressed in this session include ice sheet-climate interactions from glacial-interglacial to millennial and centennial time scales, the role of ice sheets in Cenozoic global cooling and the mid-Pleistocene transition, reconstructions of past ice sheets and sea level, the current and future evolution of the ice sheets, and the role of ice sheets in abrupt climate change.